Endocrine Abstracts

Introduction: The reccurence rate after successful neurosurgery for patients with Cushing’s disease (CD) varies between 10% and 65%. It is shown earlier that some features are associated with the probability of recurrence, yet no rules were elaborated how to analyse the set of variables.Materials and methods: The retrospective study was based on 219 cases of CD (32 men, 187 women) with a disease duration ranged from 4 months to 22 years, who underwe...

Objective: The search for the predictors of the Cushing’s disease (CD) recurrence after surgical treatment among the following parameters - gender, age, adenoma size, preoperative levels of ACTH (morning) and cortisol (evening) in the blood, postoperative levels of ACTH (morning) and cortisol (morning) in the blood.Material and methods: A retro- and prospective monocenter study of treatment outcomes in 181 patients with confirmed diagnosis of Cushin...

Abstract: Transsphenoidal surgery is the treatment of choice for Cushing’s disease. Despite the 70–90% remission rates relapses after successful transnasal adenectomy are frequently observed.Aim: To evaluate the dynamics of intra- and early postoperative levels of adrenocorticotrophic hormone (ACTH) and cortizol and their role as predictors or Cushing’s disease remission.Materials/methods: Fifty patients with Cushing...